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A Randomized, Controlled Crossover Study of the NuStep on Lower Limb Impairment and Function in Stroke (Research Summary)

Stephen J. Page, Ph.D., Senior Investigator

Stroke is the leading cause of disability in the United States, with most survivors exhibiting motor disabilities that persist over the lifetime, and usually compromise ability to perform activities of daily living (ADLs) and quality of life.

Results from our lab and others show that more affected limb training regimens can significantly improve function and reduce impairment. Because a single neural mechanism is thought to control spatial and temporal aspects of both limbs, researchers have consistently reported that bilateral training is greatly preferred throughout the lifespan. This is because, when performing a movement together, the two limbs are automatically spatially and temporally constrained such that they behave as a coordinated unit.

It has also been speculated that bilateral practice may facilitate coactivation and interhemispheric activation for asymmetric movements to be more easily developed, which could elicit functional improvements on the more affected side.

Using a multiple baseline, pre-post, randomized controlled design, this study evaluates the efficacy of the NuStep in reducing impairment and improving balance and walking-related variables in individuals > 6 months post stroke.

We hypothesize that this recumbent, bilateral training strategy will result in greater reductions in impairment and improvements in function than a control intervention.

For more information email Stephen J. Page at pagesj@ucmail.uc.