International Journal of MS Care
Lara A. Pilutti, PhD, John E. Paulseth MD, Carin Dove MD, Shucui Jiang MD PhD, Michel P. Rathbone MD PhD, and Audrey L. Hicks PhD
There is evidence of the benefits of exercise training in multiple sclerosis (MS); however, few studies have been conducted in individuals with progressive MS and severe mobility impairment. A potential exercise rehabilitation approach is total-body recumbent stepper training (TBRST). We evaluated the safety and participant-reported experience of TBRST in people with progressive MS and compared the efficacy of TBRST with that of body weight–supported treadmill training (BWSTT) on outcomes of function, fatigue, and health-related quality of life (HRQOL).